News : 2013

{image-title}

Understanding Alzheimer’s disease and the development of effective therapies

Margaret A. Pericak-Vance, Ph.D., Dr. John T. Macdonald Foundation Professor of Human Genomics and Director of the John P. Hussman Institute for Human Genomics, wrote an article for the “Black Healthcare Issue” of Legacy, a printed supplement to The Miami Herald, that explained why African Americans should participate in Alzheimer’s disease genetic research.

Read more »

{image-title}

Hussman Institute Researchers Collaborate on First Genomic Survey of Multiple Hispanic Populations

A study co-led at the Miller School by Eden Martin, Ph.D., professor in the Dr. John T. Macdonald Foundation Department of Human Genetics, has identified a wide diversity of ancestry within and between Hispanic populations, findings that could lead to more targeted gene discovery for the group.

Read more »

Eden Martin, Ph.D.

Hussman Institute Researchers Collaborate on First Genomic Survey of Multiple Hispanic Populations

A study co-led at the Miller School by Eden Martin, Ph.D., professor in the Dr. John T. Macdonald Foundation Department of Human Genetics, has identified a wide diversity of ancestry within and between Hispanic populations, findings that could lead to more targeted gene discovery for the group.

Read more »

{image-title}

International Collaboration Finds 11 New Alzheimer’s Genes to Target for Drug Discovery

Study yields fresh look at role of immune system in Alzheimer’s

Read more »

The Miller School’s IGAP team includes, from left, John R. Gilbert, Ph.D., Gary Beecham, Ph.D., Eden R. Martin, Ph.D., Brian Kunkle, Ph.D., Margaret A. Pericak-Vance, Ph.D., and Kara Hamilton-Nelson. Not pictured is  Amanda Meyers, Ph.D.

International Collaboration Finds 11 New Alzheimer’s Genes to Target for Drug Discovery

University of Miami Miller School of Medicine researchers played a key role in the largest international Alzheimer’s disease genetics collaboration to date, which identified 11 new regions of the genome that contribute to late-onset Alzheimer’s disease, doubling the number of potential genetics-based therapeutic targets to investigate.

Read more »

{image-title}

Genome-wide Study Brings MS Landscape Into Sharper Focus

In an interview with the Multiple Sclerosis Discovery Forum, Jacob McCauley, Ph.D., explained how the IMSGC team used ImmunoChip to identify 48 new genetic variations associated with MS

Read more »

Zane Zeier, Ph.D, Claes Wahlestedt, M.D., Ph.D., and Michael Benatar, M.D., Ph.D.

Defense Department Awards ALS Drug Development Grant to Miller School Researchers

A new drug development grant from the U.S. Department of Defense will allow researchers at the University of Miami Miller School of Medicine to study potential treatments for amyotrophic lateral sclerosis (ALS), a neurological degenerative condition commonly called Lou Gehrig’s disease.

Read more »

{image-title}

Researchers Uncover 48 New Genetic Variants Associated with Multiple Sclerosis

Study brings to 110 known risk factors and provides important insight into disease mechanism

Read more »

{image-title}

FDA Honors R. Rodney Howell As Hero of Rare Diseases

R. Rodney Howell, M.D., professor and chair emeritus of pediatrics who champions disease prevention through newborn screenings, has been recognized by the U.S. Food and Drug Administration as a “Rare Disease Hero.”

Read more »

{image-title}

Internship immerses students in medical research

The Knight Foundation recently posted an article on their Blog Site about this year’s JJ Vance Summer Internship please follow the link to read more!

Read more »

{image-title}

Vancover Island family hopes young mother's death from rare disorder can help others

The Vancouver Sun ran a story about one of our former participants who recently died from thrombotic storm, a rare blood clotting disorder, and the HIHG’s thrombotic storm research. It discussed how by participating in our study, Karen Roberts and her family may be able to help others. It also included an interview with the HIHG’s Margaret A. Pericak-Vance, Ph.D., and Jeffery M. Vance, M.D., Ph.D.

Read more »

{image-title}

Hussman Institute Hosts Gifted High School Students for JJ Vance Memorial Internship

The John P. Hussman Institute for Human Genomics at the Miller School hosted eight high school interns for the 2013 JJ Vance Memorial Summer Internship in the Biological and Computational Sciences, which offers rising seniors from Miami-area high schools a unique opportunity to be directly involved in scientific research

Read more »

2013 JJ Vance Memorial Summer Interns are, back row, from left, Kevin Clark, Kassala Collington, Sachin Parekh, and Michael Ivory, and front row, from left, Julie Luo, Briana Ramirez, Tiffanie Henriquez, and Isabelle Csete.

Hussman Institute Hosts Gifted High School Students for JJ Vance Memorial Internship

The John P. Hussman Institute for Human Genomics at the Miller School hosted eight high school interns for the 2013 JJ Vance Memorial Summer Internship in the Biological and Computational Sciences, which offers rising seniors from Miami-area high schools a unique opportunity to be directly involved in scientific research.

Read more »

R. Rodney Howell, M.D.

FDA Honors R. Rodney Howell As Hero of Rare Diseases

R. Rodney Howell, M.D., professor and chair emeritus of pediatrics who champions disease prevention through newborn screenings, has been recognized by the U.S. Food and Drug Administration as a “Rare Disease Hero.”

Read more »

{image-title}

Why We Can’t Wait: A Public Health Approach to Health Disparities in Genomic Medicine

Muin Khoury, M.D., Ph.D., director of the Office of Public Health Genomics at the Centers for Disease Control and Prevention, wrote about health disparities in genomic medicine and the Conference to Eliminate Health Disparities in Genomic Medicine that the John P. Hussman Institute for Human Genomics co-organized with Stanford University on the CDC’s Genomics and Health Impact blog.

Read more »

Marjana Tomic-Canic, Ph.D.

Wound Healing Pioneer Appointed to NIH’s Nursing Research Advisory Council

The Miller School’s Marjana Tomic-Canic, Ph.D., professor of dermatology and cutaneous surgery and director of the Wound Healing and Regenerative Medicine Research Program, has been appointed to the national advisory council of the NIH’s National Institute of Nursing Research.

Read more »

Margaret Pericak-Vance, Ph.D., third from left, with members of the Hussman Institute's outreach team, from left, Larry Deon Adams, Doris Caldwell, and Krystal Murphy.

Researchers Identify New Gene Associated with Alzheimer’s Disease in African Americans

Miller School researchers collaborated with an international team to identify a new gene associated with Alzheimer’s disease in African Americans. Published April 10 in the prestigious Journal of the American Medical Association, their study provides new directions for biological, genetic and therapeutic studies of Alzheimer’s disease.

Read more »

Mustafa Tekin, M.D.

Researchers Identify Gene that Causes Deafness and Myopia

Miller School researchers co-led an international study to identify a new genetic syndrome characterized by deafness, the most common human sensory disorder, and myopia (nearsightedness), the most common human eye disorder. Published online April 1 in the Journal of Clinical Investigation, the study demonstrates that the SLITRK6 protein plays a critical role in the development of normal hearing and vision in humans and mice.

Read more »

Mustafa Tekin, M.D.

Human Genetics Faculty Awarded $3.1 Million NIH Grant To Study Hearing Loss

Mustafa Tekin, M.D., associate professor in the Dr. John T. Macdonald Foundation Department of Human Genetics and member of the John P. Hussman Institute for Human Genomics, has been awarded a $3.1 million, five-year grant from the National Institutes of Health to identify genes that cause deafness and are associated with inner ear anomalies.

Read more »

From left are William K. Scott, Ph.D., Margaret Pericak-Vance, Ph.D., Stephen G. Schwartz, M.D., M.B.A., and Jaclyn L. Kovach, M.D.

Researchers Identify Seven New Genes Associated with Macular Degeneration

Researchers from the Miller School of Medicine collaborated with an international team to identify seven new genes associated with age-related macular degeneration (AMD), the most common form of vision loss in older people. Published in Nature Genetics, their study provides new directions for biological, genetic and therapeutic studies of macular degeneration.

Read more »

Jeffery M. Vance, M.D., Ph.D., and Karen Nuytemans, Ph.D.

UM Researchers Sequence Rare Variants Associated With Parkinson Disease

Miller School researchers have conducted whole exome sequencing to further investigate genes recently identified as being associated with Parkinson disease. The findings of their study, “Whole exome sequencing of rare variants in EIF4G1 and VPS35 in Parkinson disease,” were published online this month in the journal Neurology.

Read more »

Xue Zhong Liu, M.D., Ph.D.

Researchers Identify Gene Linked to Progressive Hearing Loss from Noise and Aging

An international team of researchers led by the Miller School’s Xue Zhong Liu, M.D., Ph.D., has identified the first gene to be associated with both noise-reduced and age-related hearing loss. The gene, P2X2, appears to be crucial to the preservation of life-long normal hearing and for protection against noise.

Read more »

Susan Halloran Blanton, Ph.D., and William K. Scott, Ph.D.

Genetics Faculty Awarded $4.3 Million to Study Cleft Lip and Advance Computational Genomics Training

Susan Halloran Blanton, Ph.D., associate professor of genetics and neurology, and William K. Scott, Ph.D., professor of human genetics, have been awarded a total of $4.3 million in grants by the National Institutes of Health.

Read more »