HIHG Centers : Genome Technology

Genome Technology

The Center for Genome Technology at the John P. Hussman Institute for Human Genomics develops and applies cutting-edge technologies and methods in research at the very frontier of uncovering the mysteries of the human genome.

The Center, led by John R. Gilbert, Ph.D., whose research interests encompass the molecular genetics of autism, Alzheimer’s disease, essential tremor, genetics of infectious disease, and other complex genetic disorders. As a molecular biologist, Gilbert’s expertise is in complex genetic disorders including, molecular genetics, gene analysis and characterization, RNA transcription and control, mutation analysis, and animal models of human disorders.

The Center’s ultimate aim is to provide the necessary technical tools and methodological “know-how” to enable a complete systems approach to the study and analysis of human disorders. Such studies include disease gene localization (genotyping), gene expression analysis, modern ultra-high-throughput next generation (NGS) sequencing and re-sequencing, and analysis of the effects of epigenetic abnormalities.

The Center employs faculty researchers, laboratory directors and personnel all with expertise in genomic and proteomic methods and technology. They provide cutting-edge technology and collaborative expertise to help establish new research collaborations and goals within the University and its departments.